cordata herb (HCW) on tauopathies, also involving calcium influx. To extend previous reports, we investigated the effects of water extracts of H. It has biological activities including protective effects against amyloid beta (Aβ) toxicity, via regulation of calcium homeostasis, in rat hippocampal cells. (Saururaceae) has long been used as a traditional herbal medicine. Huh, Eugene Kim, Hyo Geun Park, Hanbyeol Kang, Min Seo Lee, Bongyong Oh, Myung SookĬognitive impairment is a result of dementia of diverse causes, such as cholinergic dysfunction and Alzheimer's disease (AD). Houttuynia cordata Improves Cognitive Deficits in Cholinergic Dysfunction Alzheimer's Disease-Like Models. Despite years of research, pharmacological interven. The cholinergic theory of aging states that dysfunction of cholinergic neurons arising from the basal forebrain and terminating in the cortex and hippocampus may be involved in the cognitive decline that occurs during aging and Alzheimer’s disease. USDA-ARS?s Scientific Manuscript database Dietary polyunsaturated fatty acids improve cholinergic transmission in the aged brain
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